Thursday, April 26, 2012

Cold Laser Therapy: Biological Effects & Clinical Applications



TO REGISTER
By email: Forward completed Registration form to info@theralase.com (After selecting 'Forward' you will be able to type into form)

By Fax: Fax completed Registration form to 1.416.447.3020

By Phone: 1.866.843.5273 ext:243
Registration Form - Cold Laser Therapy: Certificate Course

Name:
Address:
City:
Province / State:
Postal / Zip Code:
Phone:
E-Mail:



Method of Payment
Cheque (payable to Theralase Inc.)
Visa:
MasterCard:
Amex:

Credit card Number:
Expiry Date:


Theralase Inc.
29 Gervais Drive suite 102
Toronto Ontario m3c1y9
Canada 

Theralase Cancer Therapy and Bacterial Destruction Technologies Presented at Major International Conferences


Toronto, Ontario -- April 26, 2012 -- Theralase Technologies Inc. (TSX-V: TLT) announced today that its innovative research on Photo Dynamic Compound (PDC) destruction of bacteria, cancer cells and solid subcutaneous (under the skin) animal tumours was recently presented at two major international scientific conferences, demonstrating the significance and validity of the research performed by Theralase’s world renowned and internationally acclaimed scientists.
On January 23, 2012 in San Francisco, California at the BiOS SPIE Photonics West Conference (the largest photonics conference in the world) Theralase presented scientific research supporting a new cost effective methodology to quickly quantify E. coli and Listeria bacteria.  This new technology would be indispensable for food manufacturing and handling facilities, restaurants, schools, nursing homes, hospitals or any organization concerned with the early detection of bacterial concentrations in food. Once these microorganisms have been quantified with this new technology, they could be quickly destroyed utilizing Theralase’s patented Photo Dynamic Compounds (PDCs) and proprietary light sources. A very simple solution that could prove invaluable to an industry plagued with food recalls that at recent estimates cost the industry over $157 billion a year in North America alone and loss of life.
On April 19, 2012 in Brussels, Belgium at the Photonic Solutions for Better Health Care (a division of Photonics Europe), Theralase presented new scientific data supporting the application of Theralase’s anti-cancer PDCs to target and effectively destroy a variety of cancer cells. The PDCs have also shown remarkable success in the complete destruction of highly aggressive tumours in preclinical, subcutaneous (under the skin) cancers in mice.
At the same conference, Theralase also unveiled to the scientific community its advanced sterilization platform technology that enables a 100% kill of life threatening infectious microorganisms, such as staphylococcus aureus also known as "golden staph”.  
Staphylococcus aureus (S. aureus) is the most potent of the many staphylococcal species in existence and is a leading cause of illness and death in humans despite the availability of numerous antibiotics. Each year, more than 500,000 patients in American hospitals contract a staphylococcal infection leading to 99,000 preventable deaths and adding an additional $35 to $45 billion in costs annually to the US healthcare system. (Source: Centers for Disease Control and Prevention).
“Theralase is committed to the early commercialization of its patented light activated Photo Dynamic Compounds (PDC) in the areas of anti-cancer and anti-bacterial applications.  This focus is being used to develop a library of first-in-class light activated compounds through various cancer and bacterial models, which are proving to be more effective in low oxygen environments, preferentially preferred by cancer cells and a number of different types of bacteria. Theralase is on the path to substantial growth and the early commercialization of our patented PDC technology in these fields, should facilitate exponential revenue increase.” said Roger Dumoulin-White, President and CEO of Theralase. He added, “Our strong PDC pipeline, one of the most innovative in the industry, has scientifically proven that our PDC technology is capable of consistently producing 100% kill levels across a wide range of bacteria and provides highly effective tumour destruction in a mouse model.  I am very proud of our scientific team and pleased that their work was recognized and acknowledged by two of the finest international academic assemblies worldwide; specifically: BiOS SPIE Photonics West and Photonics Europe.”
About Theralase Technologies Inc.:
Theralase Technologies Inc., founded in 1995, designs, develops, manufactures and markets patented, superpulsed laser technology utilized in biostimulation and biodestruction applications. Theralase technology is safe and effective in treating pain, inflammation and for tissue regeneration of neural muscular skeletal conditions and wound healing. Theralase is currently developing patented Photo Dynamic Compounds (PDCs) that are able to target and destroy cancers, bacteria and viruses when light activated by Theralase’s proprietary and patented laser technology.
For further information please visit www.theralase.com, regulatory filings may be viewed by visiting www.sedar.com.  
This press release contains forward-looking statements which reflect the Company's current expectations regarding future events. The forward-looking statements involve risks and uncertainties. Actual results could differ materially from those projected herein. The Company disclaims any obligation to update these forward-looking statements.
Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchanges) accepts responsibility for the adequacy or accuracy of this release.

Thursday, April 19, 2012

Theralase Reports Expanded Cancer Drug Technology


Toronto, Ontario -- April 19, 2012 -- Theralase Technologies Inc. (TSX-V: TLT) announced today that it has been issued a new U.S. Patent that expands the scope and capabilities of its cancer-fighting proprietary Photo Dynamic Compound (PDC) technology. The patent provides Theralase with exclusive rights to a new and advanced class of anti-cancer and anti-bacterial compounds until 2031.
Theralase continues to expand its intellectual property holdings of cancer-fighting drug compounds employed in conjunction with its proprietary therapeutic laser device capabilities. The newly issued U.S. Patent expands the Company’s capability to jointly employ its proprietary PDC and laser technologies in the destruction of a diverse variety of common cancers, bacteria and viruses. The new PDC patent identifies a special class of proprietary Photo Dynamic Compounds that can be employed in the destruction of bulk tumours.
Theralase recently reported that the growth of subcutaneous (under the skin) colon cancer tumours in mouse subjects, which were simultaneously treated with the Theralase anti-cancer PDC technologies have continued to thrive cancer-free for more than 55 days post-treatment and without any side effects.
Based on the Company’s recent successes in the research and development of its portfolio of patented PDCs, there is increased confidence that applications can be made to the regulatory bodies for human trials in the relatively near future.  
About Theralase Technologies Inc.:
Theralase Technologies Inc., founded in 1995, designs, develops, manufactures and markets patented, superpulsed laser technology utilized in biostimulation and biodestruction applications. Theralase technology is safe and effective in treating pain, inflammation and for tissue regeneration of neural muscular skeletal conditions and wound healing. Theralase is currently developing patented Photo Dynamic Compounds (PDCs) that are able to target and destroy cancers, bacteria and viruses when light activated by Theralase’s proprietary and patented laser technology.
For further information please visit www.theralase.com, regulatory filings may be viewed by visiting www.sedar.com.  
This press release contains forward-looking statements which reflect the Company's current expectations regarding future events. The forward-looking statements involve risks and uncertainties. Actual results could differ materially from those projected herein. The Company disclaims any obligation to update these forward-looking statements.
Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchanges) accepts responsibility for the adequacy or accuracy of this release.
For More Information:

Roger Dumoulin-White
President & Chief Executive Officer
416-447-8455 ext. 225
rwhite@theralase.com

Kristina Hachey
Chief Financial Officer
416-447-8455 ext. 224
khachey@theralase.com

Arkady Mandel
Chief Scientific Officer
416-447-8455 ext. 242

Greg Bewsh
Director of Investor Relations
416-447-8455 ext. 262
gbewsh@theralase.com 

Wednesday, April 11, 2012

Theralase Study Points to Cancer Breakthrough


The company's photodynamic therapy treatments destroyed tumors and prevented any recurrence.
Cells living and dead
Cells living and dead
Photodynamic therapy (PDT) is a potential treatment regime for a number of conditions. It involves introducing particular light-sensitive chemical species into biological systems, inducing them to localize at the point of interest, and then irradiating them with a light source.
It holds particular promise as a treatment to combat certain cancers, and the latest results from trials using a system developed by Ontario-based Theralase have shown that PDT was able to completely destroy subcutaneous colon cancer tumors in a mouse model. Four weeks after treatment, the mice remained free of cancer.
"The achievement of this important milestone signifies that Theralase's leading drug candidate is effective in the destruction of cancer in a live animal model and can prevent the cancer from recurring," commented Roger White of Theralase. "We are confident that Theralase is well positioned to expedite the required steps to initiate human trials in the near future."
Those trials could begin as soon as next year. White envisages a clinical road map in which a three-stage program of FDA-moderated human clinical trials could start in 2013, and be completed in 2019.
Therapeutic and oncology markets
Theralase is a developer of FDA-approved therapeutic medical lasers for treatment of chronic pain, neural muscular skeletal conditions and wound care. But alongside work in these sectors, the company has also patented light-sensitive photodynamic compounds (PDCs) for use in PDT.
"The company first entered the PDC space a little less than eight years ago, when it licensed some PDCs from a university researcher, and has been working on developing them since then," White told optics.org. "Theralase is expert at designing, manufacturing and distributing medical laser systems; our PDC researchers are experts at designing and synthesizing PDCs; and colleagues at Princess Margaret Hospital, home of the Ontario Cancer Institute, are experts at testing our PDCs and lasers through in-vitro and in-vivo pre-clinical and eventually clinical models."
Despite its simplicity in principle, PDT is not a trivial operation. The treatment is thought to work when the photosensitizer in the tumor absorbs the light and produces an active singlet-state oxygen molecule, an aggressive species which reacts with and kills the tumor cells.
But arranging for suitable PDCs to be present and localized in a tumor without being dealt with first by the body's own immune system is a challenge. In addition, only recent developments in endoscopic light-delivery systems have made subcutaneous tumors realistically treatable, and also broadened the range of potential wavelengths and matching photosensitizers.
"The wavelength of the source is of course critical, as are the average power, peak power, frequency, fluence and fluence distribution," noted White. "Some of the laser sources used in the research are proprietary to Theralase, and have been custom designed to match the characteristics of the PDCs and hence optimize activation."
The two apparently disparate sectors in which Theralase now operates are not so different for the company, according to White, who believes that the expertise gained should stand Theralase in good stead for continuing moves in these and other markets: "The therapeutic market and oncology market are two different animals; however, our experience in working with the medical community prepares us to work in the various disciplines of medicine."